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Huntingtin localisation studies - a technical review

It is well recognised that there are pitfalls when defining the subcellular localisation of a protein with immunocytochemistry. Accurate protein localisation to particular cellular micro-architecture is crucial in defining its role within the cell. Huntingtin (HTT), the protein mutated in the neurod...

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Detalhes bibliográficos
Main Authors: Hughes, Alis, Jones, Lesley
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037564/
https://ncbi.nlm.nih.gov/pubmed/21339845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1211
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