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A Small Molecule That Disrupts G-Quadruplex DNA Structure and Enhances Gene Expression

It has been hypothesized that the formation of G-quadruplex structures in the DNA of gene promoters may be functionally linked to transcription and consequently that small molecules that interact with such G-quadruplexes may modulate transcription. We previously reported that triarylpyridines are a...

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Detalhes bibliográficos
Main Authors: Waller, Zoë A. E., Sewitz, Sven A., Hsu, Shang-Te Danny, Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037543/
https://ncbi.nlm.nih.gov/pubmed/19689109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja901892u
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