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A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge.

We have examined the capacity of a live avirulent mutant form of the intracellular bacterial pathogen Legionella pneumophila to induce immune responses and protective immunity in guinea pigs. The mutant L. pneumophila is nonlethal to guinea pigs and does not revert to virulence with passage through...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Blander, S J, Breiman, R F, Horwitz, M A
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113962
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