A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge.
We have examined the capacity of a live avirulent mutant form of the intracellular bacterial pathogen Legionella pneumophila to induce immune responses and protective immunity in guinea pigs. The mutant L. pneumophila is nonlethal to guinea pigs and does not revert to virulence with passage through...
Guardado en:
| Publicado en: | J Clin Invest |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1989
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646318/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113962 |
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