A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge.

We have examined the capacity of a live avirulent mutant form of the intracellular bacterial pathogen Legionella pneumophila to induce immune responses and protective immunity in guinea pigs. The mutant L. pneumophila is nonlethal to guinea pigs and does not revert to virulence with passage through...

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Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Blander, S J, Breiman, R F, Horwitz, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646318/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113962
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