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Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.

A recently described peptide hormone, endothelin, is a potent vasoconstrictor, but it is unclear whether endothelin has other biological actions. These experiments extend the range of biological actions of endothelin to stimulation of mitogenesis. Endothelin at low concentrations (0.1-10 nM) induced...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Simonson, M S, Wann, S, Mené, P, Dubyak, G R, Kester, M, Nakazato, Y, Sedor, J R, Dunn, M J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303732/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113935
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