Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells.

A recently described peptide hormone, endothelin, is a potent vasoconstrictor, but it is unclear whether endothelin has other biological actions. These experiments extend the range of biological actions of endothelin to stimulation of mitogenesis. Endothelin at low concentrations (0.1-10 nM) induced...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Simonson, M S, Wann, S, Mené, P, Dubyak, G R, Kester, M, Nakazato, Y, Sedor, J R, Dunn, M J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303732/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113935
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