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Expanding the concept of chemically programmable antibodies to RNA-aptamers: a novel class of chemically programmed biotherapeutics

Chemically programmed antibodies represent a new class of biologic drugs that acquire their specificity through chemistry rather than through biology. To date, this approach has used small molecules and peptides to direct targeting and to extend the pharmacokinetics and otherwise enhance the biologi...

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Autors principals: Wuellner, Ulrich, Gavrilyuk, Julia I., Barbas, Carlos F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037263/
https://ncbi.nlm.nih.gov/pubmed/20645365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201001736
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