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Chemically Programmed Antibodies As HIV-1 Attachment Inhibitors

[Image: see text] Herein, we describe the design and application of two small-molecule anti-HIV compounds for the creation of chemically programmed antibodies. N-Acyl-β-lactam derivatives of two previously described molecules BMS-378806 and BMS-488043 that inhibit the interaction between HIV-1 gp120...

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Detalhes bibliográficos
Main Authors: Sato, Shinichi, Inokuma, Tsubasa, Otsubo, Nobumasa, Burton, Dennis R., Barbas, Carlos F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673733/
https://ncbi.nlm.nih.gov/pubmed/23750312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400097z
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