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Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells

Chronic myeloid leukemia (CML) results from expression of the BCR/ABL oncogene in a primitive hematopoietic cell. However BCR/ABL-activated signaling mechanisms are dependent on the cellular context in which it is expressed, and mechanisms underlying primitive human hematopoietic cell transformation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Modi, Hardik, Li, Liang, Chu, Su, Rossi, John, Yee, Jiing-Kuan, Bhatia, Ravi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036781/
https://ncbi.nlm.nih.gov/pubmed/21072043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.257
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