Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells

Lignende værker

• Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells
  af: Modi, Hardik, et al.
  Udgivet: (2007)
• SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl
  af: Chen, Jing, et al.
  Udgivet: (2007)
• Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis
  af: Yuan, Hongfeng, et al.
  Udgivet: (2012)
• A critical role for SHP2 in STAT5 activation and growth factor–mediated proliferation, survival, and differentiation of human CD34(+) cells
  af: Li, Liang, et al.
  Udgivet: (2011)
• Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene
  Udgivet: (1995)