Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis

BACKGROUND: Remodeling of lung tissues during the process of granuloma formation requires significant restructuring of the extra-cellular matrix and cathepsins K, L and S are among the strongest extra-cellular matrix degrading enzymes. Cathepsin K is highly expressed in various pathological granulom...

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Detaylı Bibliyografya
Asıl Yazarlar: Samokhin, Andriy O, Gauthier, Jacques Yves, Percival, M David, Brömme, Dieter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036631/
https://ncbi.nlm.nih.gov/pubmed/21251246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-13
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