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Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis
BACKGROUND: Remodeling of lung tissues during the process of granuloma formation requires significant restructuring of the extra-cellular matrix and cathepsins K, L and S are among the strongest extra-cellular matrix degrading enzymes. Cathepsin K is highly expressed in various pathological granulom...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3036631/ https://ncbi.nlm.nih.gov/pubmed/21251246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-13 |
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