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Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.

To investigate the effects of D-penicillamine (D-Pen) on angiogenesis, we have studied the effects of this drug on in vitro proliferation of human endothelial cells (EC) and in vivo corneal neovascularization. D-Pen, in the presence of copper sulfate, suppressed tritiated thymidine ([3H]TdR) incorpo...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Matsubara, T, Saura, R, Hirohata, K, Ziff, M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2463265/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113853
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