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Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.

To investigate the effects of D-penicillamine (D-Pen) on angiogenesis, we have studied the effects of this drug on in vitro proliferation of human endothelial cells (EC) and in vivo corneal neovascularization. D-Pen, in the presence of copper sulfate, suppressed tritiated thymidine ([3H]TdR) incorpo...

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Bibliographic Details
Main Authors: Matsubara, T, Saura, R, Hirohata, K, Ziff, M
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC303656/
https://ncbi.nlm.nih.gov/pubmed/2463265
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