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Inhibition of mitogen-induced blastogenesis in human lymphocytes by T-2 toxin and its metabolites.

Concentrations of T-2, HT-2, 3'-OH T-2, 3'-OH HT-2, T-2 triol, and T-2 tetraol toxins which inhibited [3H]thymidine uptake in mitogen-stimulated human peripheral lymphocytes by 50% were 1.5, 3.5, 4.0, 50, 150, and 150 ng/ml, respectively. The results suggested that the initial hydrolysis of T-2 toxi...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: Forsell, J H, Kateley, J R, Yoshizawa, T, Pestka, J J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4015090/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.49.6.1523-1526.1985
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