Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.

To investigate the effects of D-penicillamine (D-Pen) on angiogenesis, we have studied the effects of this drug on in vitro proliferation of human endothelial cells (EC) and in vivo corneal neovascularization. D-Pen, in the presence of copper sulfate, suppressed tritiated thymidine ([3H]TdR) incorpo...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Matsubara, T, Saura, R, Hirohata, K, Ziff, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303656/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2463265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113853
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