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In silico analysis of alpha1-antitrypsin variants: The effects of a novel mutation

Alpha1-antitrypsin (AAT) is a highly polymorphic protein with more than 120 variants that are classified as normal (normal protein secretion), deficient (reduced circulating AAT level caused by defective secretion) or null (no protein secretion). Alpha1-antitrypsin deficiency, one of the most common...

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Detalhes bibliográficos
Main Authors: Denden, Sabri, Leban, Nadia, Hayek, Donia, Knani, Jalel, Chibani, Jemni Ben, Khelil, Amel Haj
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036143/
https://ncbi.nlm.nih.gov/pubmed/21637569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572010005000089
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