Alpha-1 antitrypsin gene polymorphism in Chronic Obstructive Pulmonary Disease (COPD)

Alpha-1-antitrypsin (AAT) plays an important role in the pathogenesis of emphysema, the pathological lesion underlying the majority of the manifestations of Chronic Obstructive Pulmonary Disease (COPD). In this study we tested the hypothesis that common AAT polymorphisms influence the risk of develo...

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Bibliografiske detaljer
Main Authors: Denden, Sabri, Khelil, Amel Haj, Knani, Jalel, Lakhdar, Ramzi, Perrin, Pascale, Lefranc, Gérard, Chibani, Jemni Ben
Format: Artigo
Sprog:Inglês
Udgivet: Sociedade Brasileira de Genética 2010
Fag:
Human and Medical Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036098/
https://ncbi.nlm.nih.gov/pubmed/21637600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572009005000107
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