The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function

Precursor T-cell acute lymphoblastic leukemia (T-ALL) remains an important challenge in pediatric oncology. Because of the particularly poor prognosis of relapses, it is vital to identify molecular risk factors allowing early and effective treatment stratification. Activating NOTCH1 mutations signif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kox, C, Zimmermann, M, Stanulla, M, Leible, S, Schrappe, M, Ludwig, W-D, Koehler, R, Tolle, G, Bandapalli, O R, Breit, S, Muckenthaler, M U, Kulozik, A E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2010
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035973/
https://ncbi.nlm.nih.gov/pubmed/20944675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.203
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