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Molecular mechanism by which palmitate inhibits PKR autophosphorylation
PKR (double-stranded RNA-activated protein kinase) is an important component of the innate immunity, antiviral and apoptotic pathways. Recently, our group found that palmitate, a saturated fatty acid, is involved in apoptosis by reducing the autophosphorylation of PKR at the Thr451 residue, however,...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035770/ https://ncbi.nlm.nih.gov/pubmed/21192654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101923r |
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