Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils.
Human neutrophils, when stimulated with phorbol myristate acetate or fMet-Leu-Phe in the presence or absence of cytochalasin B, released metalloproteinases that catalytically inactivated the plasma serine proteinase inhibitor, alpha 1-antitrypsin. Inactivation, measured as loss of elastase inhibitor...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303567/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2841359/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113651 |
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