Role of HDAC3 on p53 Expression and Apoptosis in T Cells of Patients with Multiple Sclerosis

BACKGROUND: Histone deacetylase 3 (HDAC3) belongs to a family of proteins which plays an important role in protein acetylation, chromatin remodeling and transcription of genes, including those that are involved in cell proliferation and cell death. While increased expression of HDAC3 is seen in neop...

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Bibliographic Details
Main Authors: Zhang, Fanglin, Shi, Yaping, Wang, Lily, Sriram, Subramaniam
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035634/
https://ncbi.nlm.nih.gov/pubmed/21346816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016795
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