Role of Stat3 in Regulating p53 Expression and Function

Loss of p53 function by mutation is common in cancer. However, most natural p53 mutations occur at a late stage in tumor development, and many clinically detectable cancers have reduced p53 expression but no p53 mutations. It remains to be fully determined what mechanisms disable p53 during malignan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Niu, Guilian, Wright, Kenneth L., Ma, Yihong, Wright, Gabriela M., Huang, Mei, Irby, Rosalyn, Briggs, Jon, Karras, James, Cress, W. Douglas, Pardoll, Drew, Jove, Richard, Chen, Jiangdong, Yu, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190305/
https://ncbi.nlm.nih.gov/pubmed/16107692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7432-7440.2005
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