Role of Stat3 in Regulating p53 Expression and Function

Loss of p53 function by mutation is common in cancer. However, most natural p53 mutations occur at a late stage in tumor development, and many clinically detectable cancers have reduced p53 expression but no p53 mutations. It remains to be fully determined what mechanisms disable p53 during malignan...

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Autors principals: Niu, Guilian, Wright, Kenneth L., Ma, Yihong, Wright, Gabriela M., Huang, Mei, Irby, Rosalyn, Briggs, Jon, Karras, James, Cress, W. Douglas, Pardoll, Drew, Jove, Richard, Chen, Jiangdong, Yu, Hua
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190305/
https://ncbi.nlm.nih.gov/pubmed/16107692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7432-7440.2005
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