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Role of HDAC3 on p53 Expression and Apoptosis in T Cells of Patients with Multiple Sclerosis

BACKGROUND: Histone deacetylase 3 (HDAC3) belongs to a family of proteins which plays an important role in protein acetylation, chromatin remodeling and transcription of genes, including those that are involved in cell proliferation and cell death. While increased expression of HDAC3 is seen in neop...

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Autors principals: Zhang, Fanglin, Shi, Yaping, Wang, Lily, Sriram, Subramaniam
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035634/
https://ncbi.nlm.nih.gov/pubmed/21346816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016795
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