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Modelling the Delta1/Notch1 Pathway: In Search of the Mediator(s) of Neural Stem Cell Differentiation

The Notch1 signalling pathway has been shown to control neural stem cell fate through lateral inhibition of mash1, a key promoter of neuronal differentiation. Interaction between the Delta1 ligand of a differentiating cell and the Notch1 protein of a neighbouring cell results in cleavage of the tran...

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Autori principali: Kiparissides, Alexandros, Koutinas, Michalis, Moss, Toby, Newman, John, Pistikopoulos, Efstratios N., Mantalaris, Athanasios
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035613/
https://ncbi.nlm.nih.gov/pubmed/21346804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014668
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