Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.

Rheumatoid factors (RFs) in humans have been studied intensively because of their association with autoimmune and lymphoproliferative diseases. Many human IgM-RFs express cross-reactive idiotypes (CRIs) and have homologous light chains, some of which are encoded by a single V kappa gene, termed V ka...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Silverman, G J, Goldfien, R D, Chen, P, Mageed, R A, Jefferis, R, Goñi, F, Frangione, B, Fong, S, Carson, D A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1988
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3136191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113620
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