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Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.

Rheumatoid factors (RFs) in humans have been studied intensively because of their association with autoimmune and lymphoproliferative diseases. Many human IgM-RFs express cross-reactive idiotypes (CRIs) and have homologous light chains, some of which are encoded by a single V kappa gene, termed V ka...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Silverman, G J, Goldfien, R D, Chen, P, Mageed, R A, Jefferis, R, Goñi, F, Frangione, B, Fong, S, Carson, D A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3136191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113620
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