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Detection of heteroplasmy in individual mitochondrial particles
Mitochondrial DNA (mtDNA) mutations have been associated with disease and aging. Since each cell has thousands of mtDNA copies, clustered into nucleoids of five to ten mtDNA molecules each, determining the effects of a given mtDNA mutation and their connection with disease phenotype is not straightf...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035356/ https://ncbi.nlm.nih.gov/pubmed/20467729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-3751-3 |
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