Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD–severe combined immunodeficiency (SCID) mice

AIMS/HYPOTHESIS: We determined whether hyperglycaemia stimulates human beta cell replication in vivo in an islet transplant model METHODS: Human islets were transplanted into streptozotocin-induced diabetic NOD–severe combined immunodeficiency mice. Blood glucose was measured serially during a 2 wee...

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Bibliografiska uppgifter
Huvudupphovsmän: Levitt, H. E., Cyphert, T. J., Pascoe, J. L., Hollern, D. A., Abraham, N., Lundell, R. J., Rosa, T., Romano, L. C., Zou, B., O’Donnell, C. P., Stewart, A. F., Garcia-Ocaña, A., Alonso, L. C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034833/
https://ncbi.nlm.nih.gov/pubmed/20936253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1919-1
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