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The Humanized NOD/SCID Mouse as a Preclinical Model to Study the Fate of Encapsulated Human Islets

Despite encouraging results in animal models, the transplantation of microencapsulated islets into humans has not yet reached the therapeutic level. Recent clinical trials using microencapsulated human islets in barium alginate showed the presence of dense fibrotic overgrowth around the microcapsule...

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Detalhes bibliográficos
Main Authors: Vaithilingam, Vijayaganapathy, Oberholzer, Jose, Guillemin, Gilles J., Tuch, Bernard E.
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923381/
https://ncbi.nlm.nih.gov/pubmed/20703439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2010.7.62
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