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The Humanized NOD/SCID Mouse as a Preclinical Model to Study the Fate of Encapsulated Human Islets

Despite encouraging results in animal models, the transplantation of microencapsulated islets into humans has not yet reached the therapeutic level. Recent clinical trials using microencapsulated human islets in barium alginate showed the presence of dense fibrotic overgrowth around the microcapsule...

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Autors principals: Vaithilingam, Vijayaganapathy, Oberholzer, Jose, Guillemin, Gilles J., Tuch, Bernard E.
Format: Artigo
Idioma:Inglês
Publicat: SBDR - Society for Biomedical Diabetes Research 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923381/
https://ncbi.nlm.nih.gov/pubmed/20703439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2010.7.62
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