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Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action

Alzheimer disease (AD) is an age-related neurodegenerative disorder characterized by progressive memory loss, inability to perform the activities of daily living and personality changes. Unfortunately, drugs effective for this disease are limited to acetylcholinesterase inhibitors that do not impact...

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Bibliografiske detaljer
Main Authors: Barone, Eugenio, Cenini, Giovanna, Di Domenico, Fabio, Martin, Sarah, Sultana, Rukhsana, Mancuso, Cesare, Murphy, Michael Paul, Head, Elizabeth, Butterfield, D. Allan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034810/
https://ncbi.nlm.nih.gov/pubmed/21193043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.12.007
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