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Autoantibodies to Endothelial Cell Surface ATP Synthase, the Endogenous Receptor for Hsp60, Might Play a Pathogenic Role in Vasculatides

BACKGROUND: Heat shock protein (hsp) 60 that provides “danger signal” binds to the surface of resting endothelial cells (EC) but its receptor has not yet been characterized. In mitochondria, hsp60 specifically associates with adenosine triphosphate (ATP) synthase. We therefore examined the possible...

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Détails bibliographiques
Auteurs principaux: Alard, Jean-Eric, Hillion, Sophie, Guillevin, Loïc, Saraux, Alain, Pers, Jacques-Olivier, Youinou, Pierre, Jamin, Christophe
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034716/
https://ncbi.nlm.nih.gov/pubmed/21326874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014654
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