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Autoantibodies to Endothelial Cell Surface ATP Synthase, the Endogenous Receptor for Hsp60, Might Play a Pathogenic Role in Vasculatides

BACKGROUND: Heat shock protein (hsp) 60 that provides “danger signal” binds to the surface of resting endothelial cells (EC) but its receptor has not yet been characterized. In mitochondria, hsp60 specifically associates with adenosine triphosphate (ATP) synthase. We therefore examined the possible...

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Detalhes bibliográficos
Main Authors: Alard, Jean-Eric, Hillion, Sophie, Guillevin, Loïc, Saraux, Alain, Pers, Jacques-Olivier, Youinou, Pierre, Jamin, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034716/
https://ncbi.nlm.nih.gov/pubmed/21326874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014654
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