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Autoantibodies to Endothelial Cell Surface ATP Synthase, the Endogenous Receptor for Hsp60, Might Play a Pathogenic Role in Vasculatides

BACKGROUND: Heat shock protein (hsp) 60 that provides “danger signal” binds to the surface of resting endothelial cells (EC) but its receptor has not yet been characterized. In mitochondria, hsp60 specifically associates with adenosine triphosphate (ATP) synthase. We therefore examined the possible...

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Hlavní autoři: Alard, Jean-Eric, Hillion, Sophie, Guillevin, Loïc, Saraux, Alain, Pers, Jacques-Olivier, Youinou, Pierre, Jamin, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034716/
https://ncbi.nlm.nih.gov/pubmed/21326874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014654
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