Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid

The hydrophobic cavity of the C-terminal domain (CTD) of HIV-1 capsid has been recently validated as potential target for antiviral drugs by peptide-based inhibitors; however, there is no report yet of any small molecule compounds that target this hydrophobic cavity. In order to fill this gap and di...

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Detaylı Bibliyografya
Asıl Yazarlar: Curreli, Francesca, Zhang, Hongtao, Zhang, Xihui, Pyatkin, Ilya, Victor, Zagorodnikov, Altieri, Andrea, Debnath, Asim K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034313/
https://ncbi.nlm.nih.gov/pubmed/21168336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.11.045
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