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Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid
The hydrophobic cavity of the C-terminal domain (CTD) of HIV-1 capsid has been recently validated as potential target for antiviral drugs by peptide-based inhibitors; however, there is no report yet of any small molecule compounds that target this hydrophobic cavity. In order to fill this gap and di...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034313/ https://ncbi.nlm.nih.gov/pubmed/21168336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.11.045 |
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