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The DNA damage response: Balancing the scale between cancer and ageing

Defects in the DNA damage response often lead to an increased susceptibility to cancer, and so the DDR presents an interesting set of novel therapeutic targets. The maintenance of genomic integrity by the DDR has also been found to be involved in the process of organismal ageing. While the removal o...

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Detalhes bibliográficos
Main Authors: Seviour, Elena G., Lin, Shiaw-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034178/
https://ncbi.nlm.nih.gov/pubmed/21191148
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