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N-Terminal Domain of the Murine Coronavirus Receptor CEACAM1 Is Responsible for Fusogenic Activation and Conformational Changes of the Spike Protein

The mouse hepatitis virus (MHV) receptor (MHVR), CEACAM1, has two different functions for MHV entry into cells: binding to MHV spike protein (S protein) and activation of the S protein to execute virus-cell membrane fusion, the latter of which is accompanied by conformational changes of the S protei...

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Bibliographic Details
Main Authors: Miura, Hideka S., Nakagaki, Keiko, Taguchi, Fumihiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC303413/
https://ncbi.nlm.nih.gov/pubmed/14671103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.1.216-223.2004
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