Conformational Changes in the Spike Glycoprotein of Murine Coronavirus Are Induced at 37°C either by Soluble Murine CEACAM1 Receptors or by pH 8

The spike glycoprotein (S) of the murine coronavirus mouse hepatitis virus (MHV) binds to viral murine CEACAM receptor glycoproteins and causes membrane fusion. On virions, the 180-kDa S glycoprotein of the MHV-A59 strain can be cleaved by trypsin to form the 90-kDa N-terminal receptor-binding subun...

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Detalhes bibliográficos
Main Authors: Zelus, Bruce D., Schickli, Jeanne H., Blau, Dianna M., Weiss, Susan R., Holmes, Kathryn V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140793/
https://ncbi.nlm.nih.gov/pubmed/12502799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.830-840.2003
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