Magnolol Inhibits LPS-induced NF-κB/Rel Activation by Blocking p38 Kinase in Murine Macrophages

This study demonstrates the ability of magnolol, a hydroxylated biphenyl compound isolated from Magnolia officinalis, to inhibit LPS-induced expression of iNOS gene and activation of NF-κB/Rel in RAW 264.7 cells. Immunohisto-chemical staining of iNOS and Western blot analysis showed magnolol to inhi...

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Detalhes bibliográficos
Main Authors: Li, Mei Hong, Kothandan, Gugan, Cho, Seung Joo, Huong, Pham Thi Thu, Nan, Yong Hai, Lee, Kun Yeong, Shin, Song Yub, Yea, Sung Su, Jeon, Young Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034113/
https://ncbi.nlm.nih.gov/pubmed/21311674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.6.353
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