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Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

Cannabinoids have long been shown to have a range of potential therapeutic effects, including antiemetic actions, analgesia, and anxiolysis. However, psychomimetic and memory disruptive side effects, as well as the potential for abuse and dependence, have restricted their clinical development. Endog...

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Hlavní autoři: Kinsey, Steven G., O'Neal, Scott T., Long, Jonathan Z., Cravatt, Benjamin F., Lichtman, Aron H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034086/
https://ncbi.nlm.nih.gov/pubmed/21145341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.12.002
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