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Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

Cannabinoids have long been shown to have a range of potential therapeutic effects, including antiemetic actions, analgesia, and anxiolysis. However, psychomimetic and memory disruptive side effects, as well as the potential for abuse and dependence, have restricted their clinical development. Endog...

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Detalhes bibliográficos
Main Authors: Kinsey, Steven G., O'Neal, Scott T., Long, Jonathan Z., Cravatt, Benjamin F., Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034086/
https://ncbi.nlm.nih.gov/pubmed/21145341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.12.002
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