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Vinylphosphonate Internucleotide Linkages Inhibit the Activity of PcrA DNA Helicase

During the past 5 years a great deal of structural and biochemical information has given us a detailed insight into the molecular mechanism of action of the PcrA DNA helicase and challenged previous notions about the molecular mechanism of action of helicases in general. Despite this wealth of infor...

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Autori principali: Bertram, Richard D., Hayes, Christopher J., Soultanas, Panos
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033775/
https://ncbi.nlm.nih.gov/pubmed/12056904
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