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Phospholipase C, Ca(2+), and calmodulin signaling are required for 5-HT(2A) receptor-mediated transamidation of Rac1 by transglutaminase

RATIONALE: Serotonin and especially serotonin 2A (5-HT(2A)) receptor signaling are important in the etiology and treatment of schizophrenia and affective disorders. We previously reported a novel 5-HT(2A) receptor effector, increased transglutaminase (TGase)-catalyzed transamidation, and activation...

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Hlavní autoři: Dai, Ying, Dudek, Nichole L., Li, Qian, Muma, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033764/
https://ncbi.nlm.nih.gov/pubmed/20717650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1984-7
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