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Phospholipase C, Ca(2+), and calmodulin signaling are required for 5-HT(2A) receptor-mediated transamidation of Rac1 by transglutaminase
RATIONALE: Serotonin and especially serotonin 2A (5-HT(2A)) receptor signaling are important in the etiology and treatment of schizophrenia and affective disorders. We previously reported a novel 5-HT(2A) receptor effector, increased transglutaminase (TGase)-catalyzed transamidation, and activation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033764/ https://ncbi.nlm.nih.gov/pubmed/20717650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1984-7 |
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