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Buprenorphine and Opioid Antagonism, Tolerance, and Naltrexone-Precipitated Withdrawal

The dual antagonist effects of the mixed-action μ-opioid partial agonist/κ-opioid antagonist buprenorphine have not been previously compared in behavioral studies, and it is unknown whether they are comparably modified by chronic exposure. To address this question, the dose-related effects of levorp...

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Détails bibliographiques
Auteurs principaux: Paronis, Carol A., Bergman, Jack
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033719/
https://ncbi.nlm.nih.gov/pubmed/21051498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.173823
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