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Lesson from the Stoichiometry Determination of the Cohesin Complex: A Short Protease Mediated Elution Increases the Recovery from Cross-Linked Antibody-Conjugated Beads

[Image: see text] Affinity purification of proteins using antibodies coupled to beads and subsequent mass spectrometric analysis has become a standard technique for the identification of protein complexes. With the recent transfer of the isotope dilution mass spectrometry principle (IDMS) to the fie...

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Detalhes bibliográficos
Main Authors: Holzmann, Johann, Fuchs, Johannes, Pichler, Peter, Peters, Jan-Michael, Mechtler, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033704/
https://ncbi.nlm.nih.gov/pubmed/21043528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100927x
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