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Optimized Elution of Daptomycin from Polymethylmethacrylate Beads

We demonstrate that xylitol can be added to polymethylmethacrylate (PMMA) bone cement to enhance the elution of daptomycin in terms of both the peak and sustained release of antibiotic. We also demonstrate that a PMMA-xylitol formulation optimized for daptomycin can be used to enhance the elution of...

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Detalhes bibliográficos
Main Authors: Weiss, Brian D., Weiss, Elizabeth C., Haggard, Warren O., Evans, Richard P., McLaren, Sandra G., Smeltzer, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612151/
https://ncbi.nlm.nih.gov/pubmed/18955530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00258-08
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