mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell mass and cell size) and cell division. The immunosuppressive drug rapamycin inhibits cell cycle progression via inhibition of mTOR; however, the signaling pathways by which mTOR r...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Fingar, Diane C., Richardson, Celeste J., Tee, Andrew R., Cheatham, Lynn, Tsou, Christina, Blenis, John
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2004
Subjects:	Cell Growth and Development
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.200-216.2004
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