mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

The mammalian target of rapamycin (mTOR) integrates nutrient and mitogen signals to regulate cell growth (increased cell mass and cell size) and cell division. The immunosuppressive drug rapamycin inhibits cell cycle progression via inhibition of mTOR; however, the signaling pathways by which mTOR r...

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Bibliografiset tiedot
Päätekijät: Fingar, Diane C., Richardson, Celeste J., Tee, Andrew R., Cheatham, Lynn, Tsou, Christina, Blenis, John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Cell Growth and Development
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC303352/
https://ncbi.nlm.nih.gov/pubmed/14673156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.200-216.2004
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